TY - JOUR
T1 - The impact of sars-cov-2 in dementia across latin america
T2 - A call for an urgent regional plan and coordinated response
AU - Ibanez, Agustin
AU - Santamaria-Garcia, Hernando
AU - Barragan, Alejandra Guerrero
AU - Kornhuber, Alexander
AU - Ton, Alyne Mendonca Marques
AU - Slachevsky, Andrea
AU - Teixeira, Antonio Lucio
AU - Meza, Beatriz Marcela Mar
AU - Serrano, Cecilia M.
AU - Cano, Carlos
AU - Gonzalez, Carolina Arias
AU - Gonzalez-Billault, Christian
AU - Butler, Christopher
AU - Bustin, Julian
AU - Duran-Aniotz, Claudia
AU - Acosta, Daisy
AU - Matallana, Diana L.
AU - Acosta-Alvear, Diego
AU - Trépel, Dominic
AU - Resende, Elisa De Paula França
AU - de Oliveira, Fabricio Ferreira
AU - Ibanez, Francisco
AU - De Felice, Fernanda G.
AU - Navarrete, Gorka
AU - Tarnanas, Ioannis
AU - Meier, Irene B.
AU - Smid, Jerusa
AU - Llibre-Guerra, Jorge
AU - Llibre-Rodriguez, Juan J.
AU - Fajersztajn, Laís
AU - Takada, Leonel Tadao
AU - Duque, Lissette
AU - de Oliveira, Maira Okada
AU - Bicalho, Maria Aparecida Camargos
AU - Behrens, María Isabel
AU - Pintado-Caipa, Maritza
AU - Parra, Mario
AU - Wilson, Maxwell Z.
AU - De La CruPuebla, Myriam
AU - Custodio, Nilton
AU - Santibanez, Rodrigo
AU - Serafim, Rodrigo Bernardo
AU - Tavares, Ronnielly Melo
AU - Escudero, Stefanie Danielle Piña
AU - Rodriguez, Tomas Leon
AU - Dawson, Walter
AU - Miller, Bruce L.
AU - Kosik, Kenneth S.
N1 - Funding Information:
The authors thank the Alzheimer’s Association (AA), the Global Brain Health Institute (GBHI-UCSF), the Tau Consortium, the National Institutes of Health/National Institute on Aging, and the Inter-American Development Bank (IDB). Authors also thanks the grant GBHI ALZ UK-20-639295, and the MULTI-PARTNER CONSORTIUM TO EXPAND DEMENTIA RESEARCH IN LATIN AMERICA (ReDLat, supported by National Institutes of Health, National Institutes of Aging [R01 AG057234], Alzheimer’s Association [SG-20-725707], Tau Consortium, and the Global Brain Health Institute). The contents of this publication are solely the responsibility of the authors and do not represent the official views of these institutions.
Funding Information:
Agustin Ibanez is partially supported by grants from CON-ICET, FONCyT-PICT 2017-1818, FONCyT-PICT 2017 1820, ANID/FONDAP/15150012, INECO Foundation, the Interamerican Development Bank (IDB), GBHI ALZ UK-20-639295, and the MULTI-PARTNER CONSORTIUM TO EXPAND DEMENTIA RESEARCH IN LATIN AMERICA (ReDLat, supported by National Institutes of Health, National Institutes of Aging [R01 AG057234], Alzheimer’s Association [SG-20-725707], Tau Consortium, and Global Brain Health Institute). Fabricio Ferreira de Oliveira has contributed by way of a grant from FAPESP - The State of São Paulo Research Foundation (grant #2015/10109-5). Alzheimer’s Society Canada and the Weston Brain Institute (to FGF), National Institute for Translational Neuroscience (INNT/Brazil) (to FGF), the Brazilian funding agencies Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) (to FGF). Elisa De Paula França Resende received funding from the Alzheimer’s Association. Alzheimer’s Association Research Grant 2018-AARG-591107 and REDI170583 (CDA). María Isabel Behrens is supported by grants from FONDECYT (Fondo de Desarrollo Científico y Tecnológico) Grant 1190958, FONDEF (Fondo de Fomento al Desarrollo Científico y Tecnológico Grant ID19I10302, and URedes URC-036/17. Andrea Slachevsky is partially supported by grants from ANID/FONDAP/15150012, ANID / Fondecyt/ 1141279. Kenneth S. Kosik has support from the Alzheimer’s Association and Tau Consortium. The contents of this publication are solely the responsibility of the authors and do not represent the official views of these Institutions. The other authors declare no conflicts of interest.
Publisher Copyright:
© 2020 The Authors.
PY - 2020
Y1 - 2020
N2 - The SARS-CoV-2 global pandemic will disproportionately impact countries with weak economies and vulnerable populations including people with dementia. Latin American and Caribbean countries (LACs) are burdened with unstable economic development, fragile health systems, massive economic disparities, and a high prevalence of dementia. Here, we underscore the selective impact of SARS-CoV-2 on dementia among LACs, the specific strain on health systems devoted to dementia, and the subsequent effect of increasing inequalities among those with dementia in the region. Implementation of best practices for mitigation and containment faces particularly steep challenges in LACs. Based upon our consideration of these issues, we urgently call for a coordinated action plan, including the development of inexpensive mass testing and multilevel regional coordination for dementia care and related actions. Brain health diplomacy should lead to a shared and escalated response across the region, coordinating leadership, and triangulation between governments and international multilateral networks.
AB - The SARS-CoV-2 global pandemic will disproportionately impact countries with weak economies and vulnerable populations including people with dementia. Latin American and Caribbean countries (LACs) are burdened with unstable economic development, fragile health systems, massive economic disparities, and a high prevalence of dementia. Here, we underscore the selective impact of SARS-CoV-2 on dementia among LACs, the specific strain on health systems devoted to dementia, and the subsequent effect of increasing inequalities among those with dementia in the region. Implementation of best practices for mitigation and containment faces particularly steep challenges in LACs. Based upon our consideration of these issues, we urgently call for a coordinated action plan, including the development of inexpensive mass testing and multilevel regional coordination for dementia care and related actions. Brain health diplomacy should lead to a shared and escalated response across the region, coordinating leadership, and triangulation between governments and international multilateral networks.
KW - Coronavirus
KW - Dementia
KW - Health system
KW - Latin American and Caribbean countries
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85101739367&partnerID=8YFLogxK
U2 - 10.1002/trc2.12092
DO - 10.1002/trc2.12092
M3 - Article
AN - SCOPUS:85101739367
SN - 2352-8737
VL - 6
JO - Alzheimer's and Dementia: Translational Research and Clinical Interventions
JF - Alzheimer's and Dementia: Translational Research and Clinical Interventions
IS - 1
M1 - e12092
ER -