TY - JOUR
T1 - Building kidney exchange programmes in Europe - An overview of exchange practice and activities
AU - Biró, Péter
AU - Haase-Kromwijk, Bernadette
AU - Andersson, Tommy
AU - Ásgeirsson, Eyjólfur Ingi
AU - Baltesová, Tatiana
AU - Boletis, Ioannis
AU - Bolotinha, Catarina
AU - Bond, Gregor
AU - Böhmig, Georg
AU - Burnapp, Lisa
AU - Cechlárová, Katarína
AU - Di Ciaccio, Paola
AU - Fronek, Jiri
AU - Hadaya, Karine
AU - Hemke, Aline
AU - Jacquelinet, Christian
AU - Johnson, Rachel
AU - Kieszek, Rafal
AU - Kuypers, Dirk R.
AU - Leishman, Ruthanne
AU - Macher, Marie Alice
AU - Manlove, David
AU - Menoudakou, Georgia
AU - Salonen, Mikko
AU - Smeulders, Bart
AU - Sparacino, Vito
AU - Spieksma, Frits C.R.
AU - Valentín, María Oliva
AU - Wilson, Nic
AU - Van Der Klundert, Joris
N1 - Publisher Copyright:
© 2019 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - Background. Considerable differences exist among the living donor Kidney Exchange Programmes (KEPs) that are in use and being built in Europe, contributing to a variation in the number of living donor transplants (Newsletter Transplant; International figures on donation and transplantation 2016). Efforts of European KEPs to exchange (best) practices and share approaches to address challenges have, however, been limited. Methods. Experts from 23 European countries, collaborating on the European Network for Collaboration on Kidney Exchange Programmes Cooperation on Science and Technology Action, developed a questionnaire to collect detailed information on the functioning of all existing KEPs in Europe, as well as their opportunities and challenges. Following a comparative analysis, results were synthesized and interpreted by the same experts. Results. The practices, opportunities and challenges reported by 17 European countries reveal that some of the 10 operating programs are mature, whereas others are in earlier stages of development. Over 1300 transplants were performed through existing KEPs up to the end of 2016, providing approximately 8% of their countries' living kidney donations in 2015. All countries report challenges to either initiating KEPs or increasing volumes. Some challenges are shared, whereas others differ because of differences in context (eg, country size, effectiveness of deceased donor program) and ethical and legal considerations (eg, regarding living donation as such, nonrelated donors, and altruistic donation). Transnational initiatives have started in Central Europe, Scandinavia, and Southern Europe. Conclusions. Exchange of best practices and shared advancement of national programs to address existing challenges, aided by transnational exchanges, may substantially improve access to the most (cost) effective treatment for the increasing number of patients suffering from kidney disease.
AB - Background. Considerable differences exist among the living donor Kidney Exchange Programmes (KEPs) that are in use and being built in Europe, contributing to a variation in the number of living donor transplants (Newsletter Transplant; International figures on donation and transplantation 2016). Efforts of European KEPs to exchange (best) practices and share approaches to address challenges have, however, been limited. Methods. Experts from 23 European countries, collaborating on the European Network for Collaboration on Kidney Exchange Programmes Cooperation on Science and Technology Action, developed a questionnaire to collect detailed information on the functioning of all existing KEPs in Europe, as well as their opportunities and challenges. Following a comparative analysis, results were synthesized and interpreted by the same experts. Results. The practices, opportunities and challenges reported by 17 European countries reveal that some of the 10 operating programs are mature, whereas others are in earlier stages of development. Over 1300 transplants were performed through existing KEPs up to the end of 2016, providing approximately 8% of their countries' living kidney donations in 2015. All countries report challenges to either initiating KEPs or increasing volumes. Some challenges are shared, whereas others differ because of differences in context (eg, country size, effectiveness of deceased donor program) and ethical and legal considerations (eg, regarding living donation as such, nonrelated donors, and altruistic donation). Transnational initiatives have started in Central Europe, Scandinavia, and Southern Europe. Conclusions. Exchange of best practices and shared advancement of national programs to address existing challenges, aided by transnational exchanges, may substantially improve access to the most (cost) effective treatment for the increasing number of patients suffering from kidney disease.
UR - http://www.scopus.com/inward/record.url?scp=85068821560&partnerID=8YFLogxK
U2 - 10.1097/TP.0000000000002432
DO - 10.1097/TP.0000000000002432
M3 - Article
C2 - 30247314
AN - SCOPUS:85068821560
SN - 0041-1337
VL - 103
SP - 1514
EP - 1522
JO - Transplantation
JF - Transplantation
IS - 7
ER -