Boundary integral formulation for the electrical response of a nerve to an extracellular stimulation

Fernando Henriquez, Carlos Jerez-Hanckes, M. D.Fernando R. Altermatt

Producción científica: Capítulo del libro/informe/acta de congresoContribución a la conferenciarevisión exhaustiva

Resumen

We present a two-dimensional boundary integral formulation of nerve impulse propagation. A nerve impulse is a potential difference across the cellular membrane that propagates along the nerve fiber. The traveling transmembrane potential is produced by the transfer of ionic species between the intra- and extra-cellular mediums. This current flux across the membrane-composed of conduction, diffusion and capacitive terms- is regulated by passive and active mechanisms that are highly complicated to describe mathematically from a microscopic point of view. Based on the Hodgkin and Huxley axon model, we propose a well-posed integral formulation based on a quasi-static approximation amenable to time-stepping schemes and discuss first results.

Idioma originalInglés
Título de la publicación alojada2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Páginas6207-6210
Número de páginas4
DOI
EstadoPublicada - 2013
Publicado de forma externa
Evento2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japón
Duración: 3 jul. 20137 jul. 2013

Serie de la publicación

NombreProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (versión impresa)1557-170X

Conferencia

Conferencia2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
País/TerritorioJapón
CiudadOsaka
Período3/07/137/07/13

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