Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water

Alessandro Poma; Antonio Guerreiro; Sarah Caygill; Ewa Moczko; Sergey Piletsky

doi:10.1039/c3ra46838k

Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water

Alessandro Poma, Antonio Guerreiro, Sarah Caygill, Ewa Moczko, Sergey Piletsky

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

91 Citas (Scopus)

Resumen

We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, "ready for use" MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.

Idioma original	Inglés
Páginas (desde-hasta)	4203-4206
Número de páginas	4
Publicación	RSC Advances
Volumen	4
N.º	8
DOI	https://doi.org/10.1039/c3ra46838k
Estado	Publicada - 2014
Publicado de forma externa	Sí

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title = "Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water",

abstract = "We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, {"}ready for use{"} MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.",

author = "Alessandro Poma and Antonio Guerreiro and Sarah Caygill and Ewa Moczko and Sergey Piletsky",

year = "2014",

doi = "10.1039/c3ra46838k",

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T1 - Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water

AU - Poma, Alessandro

AU - Guerreiro, Antonio

AU - Caygill, Sarah

AU - Moczko, Ewa

AU - Piletsky, Sergey

PY - 2014

Y1 - 2014

N2 - We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, "ready for use" MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.

AB - We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, "ready for use" MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.

UR - http://www.scopus.com/inward/record.url?scp=84890839679&partnerID=8YFLogxK

U2 - 10.1039/c3ra46838k

DO - 10.1039/c3ra46838k

M3 - Article

AN - SCOPUS:84890839679

SN - 2046-2069

VL - 4

SP - 4203

EP - 4206

JO - RSC Advances

JF - RSC Advances

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ER -

Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water

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