TY - JOUR
T1 - Argentina's early contributions to the understanding of frontotemporal lobar degeneration
AU - Barutta, Joaquín
AU - Hodges, John
AU - Ibáñez, Agustín
AU - Gleichgerrcht, Ezequiel
AU - Manes, Facundo
N1 - Funding Information:
This research was partially supported by a FINECO grant and by a Fundacion LyD grant. John Hodges is supported by an Australian Research Council Federation grant. The authors declare that they have no competing financial interests.
PY - 2011/5
Y1 - 2011/5
N2 - Over a 100 years have passed since Pick's description of what is now termed frontotemporal lobar degeneration (FTLD). FTLD is a topic of intense current research interest yet some relevant contributions by non-English speaking authors have received little attention, which makes the history of FTLD research incomplete. In the hopes of filling some of the gaps in the history of FTLD research, the present article introduces fundamental work carried out in Argentina during the first half of the 20th century by Christfried Jakob and Braulio A. Moyano. Jakob's neurophilosophy, as well as his empirical descriptions on dementia and theoretic insights into the role of the frontal lobes are highlighted. Moyano's works on frontotemporal dementia (FTD), specifically concerning language deficits and the concept of focal pathology in Alzheimer disease presenting with progressive aphasia are introduced. These early contributions are examined in the light of the current knowledge on FTLD, highlighting some of the authors' early original contributions, as well as their misconceptions. These authors remain largely unknown despite the fact that their contributions were fundamental in kindling interest in behavioral neurology in Latin America, which continues to this day.
AB - Over a 100 years have passed since Pick's description of what is now termed frontotemporal lobar degeneration (FTLD). FTLD is a topic of intense current research interest yet some relevant contributions by non-English speaking authors have received little attention, which makes the history of FTLD research incomplete. In the hopes of filling some of the gaps in the history of FTLD research, the present article introduces fundamental work carried out in Argentina during the first half of the 20th century by Christfried Jakob and Braulio A. Moyano. Jakob's neurophilosophy, as well as his empirical descriptions on dementia and theoretic insights into the role of the frontal lobes are highlighted. Moyano's works on frontotemporal dementia (FTD), specifically concerning language deficits and the concept of focal pathology in Alzheimer disease presenting with progressive aphasia are introduced. These early contributions are examined in the light of the current knowledge on FTLD, highlighting some of the authors' early original contributions, as well as their misconceptions. These authors remain largely unknown despite the fact that their contributions were fundamental in kindling interest in behavioral neurology in Latin America, which continues to this day.
KW - Argentina
KW - Braulio Moyano
KW - Christfried Jakob
KW - Frontotemporal lobar degeneration
UR - http://www.scopus.com/inward/record.url?scp=79952709815&partnerID=8YFLogxK
U2 - 10.1016/j.cortex.2010.05.006
DO - 10.1016/j.cortex.2010.05.006
M3 - Article
C2 - 20579637
AN - SCOPUS:79952709815
SN - 0010-9452
VL - 47
SP - 621
EP - 627
JO - Cortex
JF - Cortex
IS - 5
ER -