TY - GEN
T1 - Vanishing "tattoo" multi-sensor for biomedical diagnostics
AU - Moczko, E.
AU - Meglinski, I.
AU - Piletsky, S.
PY - 2008
Y1 - 2008
N2 - Currently, precise non-invasive diagnostics systems for the real-time multi detection and monitoring of physiological parameters and chemical analytes in the human body are urgently required by clinicians, physiologists and bio-medical researchers. We have developed a novel cost effective smart 'vanishing tattoo' (similar to temporary child's tattoos) consisting of environmental-sensitive dyes. Painlessly impregnated into the skin the smart tattoo is capable of generating optical/fluorescence changes (absorbance, transmission, reflectance, emission and/or luminescence within UV, VIS or NIR regions) in response to physical or chemical changes. These changes allow the identification of colour pattern changes similar to bar-code scanning. Such a system allows an easy, cheap and robust comprehensive detection of various parameters and analytes in a small volume of sample (e.g. variations in pH, temperature, ionic strength, solvent polarity, presence of redox species, surfactants, oxygen). These smart tattoos have possible applications in monitoring the progress of disease and transcutaneous drug delivery. The potential of this highly innovative diagnostic tool is wide and diverse and can impact on routine clinical diagnostics, general therapeutic management, skin care and cosmetic products testing as well as fundamental physiological investigations.
AB - Currently, precise non-invasive diagnostics systems for the real-time multi detection and monitoring of physiological parameters and chemical analytes in the human body are urgently required by clinicians, physiologists and bio-medical researchers. We have developed a novel cost effective smart 'vanishing tattoo' (similar to temporary child's tattoos) consisting of environmental-sensitive dyes. Painlessly impregnated into the skin the smart tattoo is capable of generating optical/fluorescence changes (absorbance, transmission, reflectance, emission and/or luminescence within UV, VIS or NIR regions) in response to physical or chemical changes. These changes allow the identification of colour pattern changes similar to bar-code scanning. Such a system allows an easy, cheap and robust comprehensive detection of various parameters and analytes in a small volume of sample (e.g. variations in pH, temperature, ionic strength, solvent polarity, presence of redox species, surfactants, oxygen). These smart tattoos have possible applications in monitoring the progress of disease and transcutaneous drug delivery. The potential of this highly innovative diagnostic tool is wide and diverse and can impact on routine clinical diagnostics, general therapeutic management, skin care and cosmetic products testing as well as fundamental physiological investigations.
KW - Biomedical diagnosis
KW - Computer simulation
KW - Fluorescence spectroscopy
KW - Fluorophores
KW - Human skin
KW - Optical multisensor
UR - http://www.scopus.com/inward/record.url?scp=44949237158&partnerID=8YFLogxK
U2 - 10.1117/12.780939
DO - 10.1117/12.780939
M3 - Conference contribution
AN - SCOPUS:44949237158
SN - 9780819471895
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Biophotonics
T2 - Biophotonics: Photonic Solutions for Better Health Care
Y2 - 8 April 2008 through 10 April 2008
ER -