TY - JOUR
T1 - Validez del diagnóstico de trastorno por déficit de atención/hiperactividad
T2 - De lo fenomenológico a lo neurobiológico (II)
AU - Trujillo-Orrego, Natalia
AU - Ibáñez, Agustín
AU - Pineda, David A.
PY - 2012
Y1 - 2012
N2 - The diagnostic criteria for the attention deficit/hyperactivity disorder (ADHD) were defined by the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders, fourth version. ADHD is a neuropsychiatric disorder associated with impairments in everyday life and behavioral dysregulation (i.e. inattention, hyperactivity and impulsivity), and it has showed empirical evidence from clinical, pharmacological, and psychometric studies. Nevertheless, the role of neurobiological impairments in the presentation of the symptoms remains unclear. For this paper, the authors reviewed Spanish and English literature that support the neurobiological validity of the disorder, aimed to present evidence associated with its cognitive and behavioral phenotype (e.g. in: neuropsychology, electrophysiology, structural and functional magnetic resonance imaging, neurochemistry and genetics). Additionally, an integrative theoretical clinical and scientific proposal is presented. Finally, the introduction of neurobiological marker as part of the definitive diagnosis is suggested, as a started point for the identification of therapeutic targets.
AB - The diagnostic criteria for the attention deficit/hyperactivity disorder (ADHD) were defined by the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders, fourth version. ADHD is a neuropsychiatric disorder associated with impairments in everyday life and behavioral dysregulation (i.e. inattention, hyperactivity and impulsivity), and it has showed empirical evidence from clinical, pharmacological, and psychometric studies. Nevertheless, the role of neurobiological impairments in the presentation of the symptoms remains unclear. For this paper, the authors reviewed Spanish and English literature that support the neurobiological validity of the disorder, aimed to present evidence associated with its cognitive and behavioral phenotype (e.g. in: neuropsychology, electrophysiology, structural and functional magnetic resonance imaging, neurochemistry and genetics). Additionally, an integrative theoretical clinical and scientific proposal is presented. Finally, the introduction of neurobiological marker as part of the definitive diagnosis is suggested, as a started point for the identification of therapeutic targets.
KW - Attentional deficit/hyperactivity disorder
KW - Cognitive neuroscience
KW - Multilevel approach
KW - Neurobiological validity
UR - http://www.scopus.com/inward/record.url?scp=84858758212&partnerID=8YFLogxK
U2 - 10.33588/rn.5406.2011145
DO - 10.33588/rn.5406.2011145
M3 - Review article
C2 - 22403150
AN - SCOPUS:84858758212
SN - 0210-0010
VL - 54
SP - 367
EP - 379
JO - Revista de Neurologia
JF - Revista de Neurologia
IS - 6
ER -