The effect of sintering temperature on the microstructure and mechanical properties of a bioceramic bone scaffold

Juan Vivanco, Josh Slane, Rick Nay, Amanda Simpson, Heidi Lynn Ploeg

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Micro and nanostructural properties are believed to play a critical role in the osteoinductive capacity of bioceramic bone scaffolds. Physical characteristics also play an important role for optimum biological performance, including osteoconductivity and strength. In this study microstructural and nano-mechanical properties of a bioceramic bone scaffold were investigated as a function of the sintering temperature in the range of 950-1150 °C, through the use of scanning electron microscopy (SEM), X-ray diffraction (XRD) and nanoindentation testing. Although the samples presented the same crystallographic phase, an increase in sintering temperature resulted in increased grain size, density and crystallite size. The intrinsic mechanical properties were measured by nanoindentation testing and analyzed with the Oliver-Pharr method. The nanoindentation tests consisted of a series of fourteen partial unload tests (n=14 per treatment) of twelve steps ranging from 1 to 12 mN. Statistically significant increases in hardness and elastic modulus were measured for increasing sintering temperature. These results support the development of clinically successful bioceramic scaffolds with mechanical properties that encourage bone ingrowth and provide structural integrity.

Original languageEnglish
Pages (from-to)2150-2160
Number of pages11
JournalJournal of the Mechanical Behavior of Biomedical Materials
Volume4
Issue number8
DOIs
StatePublished - Nov 2011
Externally publishedYes

Keywords

  • Bioceramic
  • Bone scaffold
  • Musculoskeletal injuries
  • Nanoindentation

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