Perspectives on biological growth and remodeling

D. Ambrosi, G. A. Ateshian, E. M. Arruda, S. C. Cowin, J. Dumais, A. Goriely, G. A. Holzapfel, J. D. Humphrey, R. Kemkemer, E. Kuhl, J. E. Olberding, L. A. Taber, K. Garikipati

Research output: Contribution to journalReview articlepeer-review

350 Scopus citations


The continuum mechanical treatment of biological growth and remodeling has attracted considerable attention over the past fifteen years. Many aspects of these problems are now well-understood, yet there remain areas in need of significant development from the standpoint of experiments, theory, and computation. In this perspective paper we review the state of the field and highlight open questions, challenges, and avenues for further development.

Original languageEnglish
Pages (from-to)863-883
Number of pages21
JournalJournal of the Mechanics and Physics of Solids
Issue number4
StatePublished - Apr 2011


  • Chemo-mechanics
  • Computational mechanics
  • Mechanotransduction
  • Morphogenesis
  • Thermodynamics


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