Optical assay for biotechnology and clinical diagnosis

Ewa Moczko, Michael Cauchi, Claire Turner, Igor Meglinski, Sergey Piletsky

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological and clinical samples. The performance of the assay is based on the analysis of spectrum of the selected fluorescent dyes with the operational principle similar to electronic nose and electronic tongue systems. This approach has been successfully applied for monitoring of growing cell cultures and identification of gastrointestinal diseases in humans.

Original languageEnglish
Article number5711652
Pages (from-to)2154-2160
Number of pages7
JournalIEEE Transactions on Biomedical Engineering
Issue number8
StatePublished - Aug 2011
Externally publishedYes


  • Chemometrics
  • clinical applications
  • fluorescence dyes
  • optical diagnosis


Dive into the research topics of 'Optical assay for biotechnology and clinical diagnosis'. Together they form a unique fingerprint.

Cite this