Optical assay for biotechnology and clinical diagnosis

Ewa Moczko; Michael Cauchi; Claire Turner; Igor Meglinski; Sergey Piletsky

doi:10.1109/TBME.2011.2113348

Optical assay for biotechnology and clinical diagnosis

Ewa Moczko, Michael Cauchi, Claire Turner, Igor Meglinski, Sergey Piletsky

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological and clinical samples. The performance of the assay is based on the analysis of spectrum of the selected fluorescent dyes with the operational principle similar to electronic nose and electronic tongue systems. This approach has been successfully applied for monitoring of growing cell cultures and identification of gastrointestinal diseases in humans.

Original language	English
Article number	5711652
Pages (from-to)	2154-2160
Number of pages	7
Journal	IEEE Transactions on Biomedical Engineering
Volume	58
Issue number	8
DOIs	https://doi.org/10.1109/TBME.2011.2113348
State	Published - Aug 2011
Externally published	Yes

Keywords

Chemometrics
clinical applications
fluorescence dyes
optical diagnosis

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10.1109/TBME.2011.2113348

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AU - Meglinski, Igor

AU - Piletsky, Sergey

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Optical assay for biotechnology and clinical diagnosis

Abstract

Keywords

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