Joint models reveal genetic architecture of pubertal stage transitions and their association with BMI in admixed Chilean population

Keyphrases

• Chilean Population 100%
• Body Mass Index 100%
• Joint Model 100%
• Genetic Architecture 100%
• Pubertal Stage 100%
• Stage Transition 100%
• Native American 50%
• Genome-wide Association Study 50%
• Tanner Stage 50%
• Chilean 25%
• Gene Regulation 25%
• Obesity 25%
• Risk Factors 25%
• Obesity Type 25%
• Psychopathology 25%
• Adulthood 25%
• Type 2 Diabetes Mellitus (T2DM) 25%
• Genetic Ancestry 25%
• Ancestry Proportion 25%
• Genetic Variants 25%
• Longitudinal Trajectories 25%
• Puberty 25%
• Pubertal Timing 25%
• Pubertal Onset 25%
• Puberty Onset 25%
• Bone Fracture 25%
• European American 25%
• Time-to-event Data 25%
• Metabolic Disorders 25%
• Expression Quantitative Trait Loci (eQTL) 25%
• Alternative Splicing 25%
• Pubertal Development 25%
• LARS2 25%
• Phenotypic Transition 25%
• Multiple Tissues 25%
• LIMD1 25%
• Growth-related Genes 25%
• SQTL 25%
• Tanner Scale 25%
• Early Puberty 25%
• Sexual Maturation 25%
• Tanner 25%
• Index Parameters 25%
• Five Stages 25%
• Ovarian Dysfunction 25%

INIS

• architecture 100%
• genes 100%
• populations 100%
• genetics 100%
• diseases 66%
• growth 66%
• obesity 66%
• splicing 66%
• data 33%
• trajectories 33%
• cancer 33%
• children 33%
• peaks 33%
• tissues 33%
• risks 33%
• maturation 33%
• ovaries 33%
• bone fractures 33%

Biochemistry, Genetics and Molecular Biology

• Body Mass 100%
• Genetic Architecture 100%
• Genome-Wide Association Study 50%
• Gene Expression 25%
• Genetics 25%
• Genetic Divergence 25%
• Cohort Study 25%
• Quantitative Trait Locus 25%