@article{80236fa5fe44494a8c794d5aff15b88e,
title = "He Jiankui´s gene-editing experiment and the non-identity problem",
abstract = "Genetic engineering has been a topic of discussion for over 50 years, but it is only recently that gene editing has become a reality. CRISPR biotechnologies have made gene editing much safer, precise and feasible. We have witnessed the first cases of human germline genetic modification resulting in live births, conducted by He Jiankui. In this paper, we will analyse He Jiankui{\textquoteright}s case in relation to one of the most difficult problems in procreative ethics (or the ethics of future generations): the non-identity problem. We believe that this analysis will help us to understand the ethics involved in gene editing and hopefully allow for a better, more philosophically grounded legislation on CRISPR and other gene-editing technologies.",
keywords = "CRISPR, He Jiankui, future people ethics, gene editing, non-identity, procreative ethics",
author = "Marcos Alonso and Julian Savulescu",
note = "Funding Information: Julian Savulescu, through his involvement with the Murdoch Children{\textquoteright}s Research Institute, received funding through from the Victorian State Government through the Operational Infrastructure Support (OIS) Program. Funding Information: This research was funded in whole, or in part, by the Wellcome Trust [Grant number WT203132/Z/16/Z; WT104848/Z/14/Z]. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. Funding Information: We thank two anonymous reviewers for many helpful and constructive comments. This research was funded in whole, or in part, by the Wellcome Trust [Grant number WT203132/Z/16/Z; WT104848/Z/14/Z]. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. Marcos Alonso received funding by FONDECYT Iniciaci{\'o}n 11200050, titled {"}Revoluci{\'o}n gen{\'e}tica e identidad personal. Una propuesta para afrontar las dificultades fundamentales de la {\'e}tica de las personas futuras{"}. Julian Savulescu, through his involvement with the Murdoch Children{\textquoteright}s Research Institute, received funding through from the Victorian State Government through the Operational Infrastructure Support (OIS) Program. Publisher Copyright: {\textcopyright} 2021 The Authors. Bioethics published by John Wiley & Sons Ltd.",
year = "2021",
month = jul,
doi = "10.1111/bioe.12878",
language = "English",
volume = "35",
pages = "563--573",
journal = "Bioethics",
issn = "0269-9702",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "6",
}