Good long-term outcome of a severe myocardial failure after peripheral blood stem cell transplantation: A case report

Paola Corti, Elena Viganò, Tiziana Coliva, Sonia Bonanomi, Haidi Sangalli, Marco Nuara, Adriana Balduzzi, Cornelio Uderzo, Attilio Rovelli

Research output: Contribution to journalArticlepeer-review

Abstract

A six-year-old girl with acute lymphoblastic leukaemia (ALL) in second remission underwent autologous peripheral blood stem cell transplantation (APBSCT). Despite normal cardiac function before autologous bone marrow transplantation, the patient was diagnosed with severe cardiac failure which was confirmed by EKG and ultrasound, showing an ejection fraction (EF) of 45%, six months after transplantation. The patient was adequately treated and periodically monitored, making a progressive improvement so that now, 62 months after the event, she conducts a normal healthy life (Lansky score: 100%) with no medication and a normal EF (61%).

Original languageEnglish
Pages (from-to)294-296
Number of pages3
JournalHAEMA
Volume8
Issue number2
StatePublished - Apr 2005
Externally publishedYes

Keywords

  • Acute lymphoblastic leukemia
  • Anthracyclines
  • Bone marrow transplantation
  • Myocardial failure
  • Total body irradiation

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