Dynamic finite-element model of axon extracellular stimulation

Fernando Henriquez; Carlos Jerez-Hanckes; M. D.Fernando R. Altermatt

doi:10.1109/NER.2013.6696003

Dynamic finite-element model of axon extracellular stimulation

Fernando Henriquez, Carlos Jerez-Hanckes, M. D.Fernando R. Altermatt

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

Abstract

We study the electrical influence of an electrode over an axon of nonzero thickness in time using a two-dimensional finite element formulation. Although our inspiration comes from the practice of peripheral nerve stimulation, other types of neural tissue excitation can benefit from the model. Our formulation combines a Hodgkin-Huxley model to account for nerve dynamics with electrostatic intra- and extracellular potentials. Thus, the influence of external electrode geometry and parameters can be addressed instead of simplifying them to point current sources. We show first numerical results for different extracellular stimuli and explore future enhancement directions.

Original language	English
Title of host publication	2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
Pages	589-592
Number of pages	4
DOIs	https://doi.org/10.1109/NER.2013.6696003
State	Published - 2013
Externally published	Yes
Event	2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 - San Diego, CA, United States Duration: 6 Nov 2013 → 8 Nov 2013

Publication series

Name	International IEEE/EMBS Conference on Neural Engineering, NER
ISSN (Print)	1948-3546
ISSN (Electronic)	1948-3554

Conference

Conference	2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
Country/Territory	United States
City	San Diego, CA
Period	6/11/13 → 8/11/13

Access to Document

10.1109/NER.2013.6696003

Cite this

@inproceedings{66b92a9e95a442878df2a22a815c26e7,

title = "Dynamic finite-element model of axon extracellular stimulation",

abstract = "We study the electrical influence of an electrode over an axon of nonzero thickness in time using a two-dimensional finite element formulation. Although our inspiration comes from the practice of peripheral nerve stimulation, other types of neural tissue excitation can benefit from the model. Our formulation combines a Hodgkin-Huxley model to account for nerve dynamics with electrostatic intra- and extracellular potentials. Thus, the influence of external electrode geometry and parameters can be addressed instead of simplifying them to point current sources. We show first numerical results for different extracellular stimuli and explore future enhancement directions.",

author = "Fernando Henriquez and Carlos Jerez-Hanckes and Altermatt, {M. D.Fernando R.}",

year = "2013",

doi = "10.1109/NER.2013.6696003",

language = "English",

isbn = "9781467319690",

series = "International IEEE/EMBS Conference on Neural Engineering, NER",

pages = "589--592",

booktitle = "2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013",

note = "2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 ; Conference date: 06-11-2013 Through 08-11-2013",

}

Henriquez, F, Jerez-Hanckes, C & Altermatt, MDFR 2013, Dynamic finite-element model of axon extracellular stimulation. in 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013., 6696003, International IEEE/EMBS Conference on Neural Engineering, NER, pp. 589-592, 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013, San Diego, CA, United States, 6/11/13. https://doi.org/10.1109/NER.2013.6696003

Dynamic finite-element model of axon extracellular stimulation. / Henriquez, Fernando; Jerez-Hanckes, Carlos; Altermatt, M. D.Fernando R.
2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013. 2013. p. 589-592 6696003 (International IEEE/EMBS Conference on Neural Engineering, NER).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Dynamic finite-element model of axon extracellular stimulation

AU - Henriquez, Fernando

AU - Jerez-Hanckes, Carlos

AU - Altermatt, M. D.Fernando R.

PY - 2013

Y1 - 2013

N2 - We study the electrical influence of an electrode over an axon of nonzero thickness in time using a two-dimensional finite element formulation. Although our inspiration comes from the practice of peripheral nerve stimulation, other types of neural tissue excitation can benefit from the model. Our formulation combines a Hodgkin-Huxley model to account for nerve dynamics with electrostatic intra- and extracellular potentials. Thus, the influence of external electrode geometry and parameters can be addressed instead of simplifying them to point current sources. We show first numerical results for different extracellular stimuli and explore future enhancement directions.

AB - We study the electrical influence of an electrode over an axon of nonzero thickness in time using a two-dimensional finite element formulation. Although our inspiration comes from the practice of peripheral nerve stimulation, other types of neural tissue excitation can benefit from the model. Our formulation combines a Hodgkin-Huxley model to account for nerve dynamics with electrostatic intra- and extracellular potentials. Thus, the influence of external electrode geometry and parameters can be addressed instead of simplifying them to point current sources. We show first numerical results for different extracellular stimuli and explore future enhancement directions.

UR - http://www.scopus.com/inward/record.url?scp=84897676373&partnerID=8YFLogxK

U2 - 10.1109/NER.2013.6696003

DO - 10.1109/NER.2013.6696003

M3 - Conference contribution

AN - SCOPUS:84897676373

SN - 9781467319690

T3 - International IEEE/EMBS Conference on Neural Engineering, NER

SP - 589

EP - 592

BT - 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013

T2 - 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013

Y2 - 6 November 2013 through 8 November 2013

ER -

Dynamic finite-element model of axon extracellular stimulation

Abstract

Publication series

Conference

Access to Document

Fingerprint

Cite this