Derivation of a bidomain model for bundles of myelinated axons

Carlos Jerez-Hanckes, Isabel A. Martínez Ávila, Irina Pettersson, Volodymyr Rybalko

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The work concerns the multiscale modeling of a nerve fascicle of myelinated axons. We present a rigorous derivation of a macroscopic bidomain model describing the behavior of the electric potential in the fascicle based on the FitzHugh–Nagumo membrane dynamics. The approach is based on the two-scale convergence machinery combined with the method of monotone operators.

Original languageEnglish
Article number103789
JournalNonlinear Analysis: Real World Applications
StatePublished - Apr 2023
Externally publishedYes


  • Bidomain model
  • Degenerate evolution equation
  • FitzHugh–Nagumo model
  • Multiscale analysis
  • Myelinated axons
  • Nerve fascicle


Dive into the research topics of 'Derivation of a bidomain model for bundles of myelinated axons'. Together they form a unique fingerprint.

Cite this