Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water

Alessandro Poma, Antonio Guerreiro, Sarah Caygill, Ewa Moczko, Sergey Piletsky

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, "ready for use" MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.

Original languageEnglish
Pages (from-to)4203-4206
Number of pages4
JournalRSC Advances
Volume4
Issue number8
DOIs
StatePublished - 2014
Externally publishedYes

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