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A Convolutional Vision Transformer with Channel Attention for Multi-Class Alzheimer's Disease Classification Using MRI

  • Mario Alejandro Bravo-Ortiz
  • , Sergio Alejandro Holguin-Garcia
  • , Ernesto Guevara-Navarro
  • , Luis Miguel Cardona-Perez
  • , Rafael Medina-Lopez
  • , Isabel Sofia Benitez Duque
  • , Reinel Tabares-Soto
  • , Gonzalo A. Ruz

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Alzheimer's disease is a progressive neurodegenerative disorder and the primary cause of dementia globally. Early and accurate diagnosis is essential for improving patient outcomes. This paper proposes a novel deep learning architecture that integrates a Convolutional Vision Transformer with Squeeze-And-Excitation blocks to classify different stages of Alzheimer's disease from MRI images. Unlike prior studies, which often merge moderate and mild dementia classes, this work evaluates the model in binary, three-class (excluding the minority class), and full four-class settings. Experimental results demonstrate that the proposed model achieves an accuracy of 99.36 %, outperforming or matching state-of-The-Art approaches even without data balancing. These results underscore the potential of combining attention mechanisms with transformer-based architectures for enhancing automated AD diagnosis and provide a promising step toward more clinically robust solutions.

Original languageEnglish
Title of host publication2025 IEEE 4th Colombian BioCAS Workshop, ColBioCAS 2025 - Conference Proceedings
EditorsJorge Ivan Marin-Hurtado
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798331565435
DOIs
StatePublished - 2025
Event4th IEEE Colombian BioCAS Workshop, ColBioCAS 2025 - Armenia, Colombia
Duration: 27 Aug 202529 Aug 2025

Publication series

Name2025 IEEE 4th Colombian BioCAS Workshop, ColBioCAS 2025 - Conference Proceedings

Conference

Conference4th IEEE Colombian BioCAS Workshop, ColBioCAS 2025
Country/TerritoryColombia
CityArmenia
Period27/08/2529/08/25

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Alzheimer's Disease
  • Convolutional Vision Transformer
  • Deep Learning

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