Claudia Duran-Aniotz

2024

Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

Moguilner, S., Baez, S., Hernandez, H., Migeot, J., Legaz, A., Gonzalez-Gomez, R., Farina, F. R., Prado, P., Cuadros, J., Tagliazucchi, E., Altschuler, F., Maito, M. A., Godoy, M. E., Cruzat, J., Valdes-Sosa, P. A., Lopera, F., Ochoa-Gómez, J. F., Hernandez, A. G., Bonilla-Santos, J. & Gonzalez-Montealegre, R. A. & 55 others, Anghinah, R., d’Almeida Manfrinati, L. E., Fittipaldi, S., Medel, V., Olivares, D., Yener, G. G., Escudero, J., Babiloni, C., Whelan, R., Güntekin, B., Yırıkoğulları, H., Santamaria-Garcia, H., Lucas, A. F., Huepe, D., Di Caterina, G., Soto-Añari, M., Birba, A., Sainz-Ballesteros, A., Coronel-Oliveros, C., Yigezu, A., Herrera, E., Abasolo, D., Kilborn, K., Rubido, N., Clark, R. A., Herzog, R., Yerlikaya, D., Hu, K., Parra, M. A., Reyes, P., García, A. M., Matallana, D. L., Avila-Funes, J. A., Slachevsky, A., Behrens, M. I., Custodio, N., Cardona, J. F., Barttfeld, P., Brusco, I. L., Bruno, M. A., Sosa Ortiz, A. L., Pina-Escudero, S. D., Takada, L. T., Resende, E., Possin, K. L., de Oliveira, M. O., Lopez-Valdes, A., Lawlor, B., Robertson, I. H., Kosik, K. S., Duran-Aniotz, C., Valcour, V., Yokoyama, J. S., Miller, B. & Ibanez, A., 2024, (Accepted/In press) In: Nature Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

Healthy aging meta-analyses and scoping review of risk factors across Latin America reveal large heterogeneity and weak predictive models

Ibanez, A., Maito, M., Botero-Rodríguez, F., Fittipaldi, S., Coronel, C., Migeot, J., Lacroix, A., Lawlor, B., Duran-Aniotz, C., Baez, S. & Santamaria-Garcia, H., Aug 2024, In: Nature Aging. 4, 8, p. 1153-1165 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Long-Term Survival and Immune Response Dynamics in Melanoma Patients Undergoing TAPCells-Based Vaccination Therapy

Tittarelli, A., Pereda, C., Gleisner, M. A., López, M. N., Flores, I., Tempio, F., Lladser, A., Achour, A., González, F. E., Durán-Aniotz, C., Miranda, J. P., Larrondo, M. & Salazar-Onfray, F., Apr 2024, In: Vaccines. 12, 4, 357.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Biomarkers for dementia in Latin American countries: Gaps and opportunities

Parra, M. A., Orellana, P., Leon, T., Victoria, C. G., Henriquez, F., Gomez, R., Avalos, C., Damian, A., Slachevsky, A., Ibañez, A., Zetterberg, H., Tijms, B. M., Yokoyama, J. S., Piña-Escudero, S. D., Cochran, J. N., Matallana, D. L., Acosta, D., Allegri, R., Arias-Suárez, B. P. & Barra, B. & 36 others, Behrens, M. I., Brucki, S. M. D., Busatto, G., Caramelli, P., Castro-Suarez, S., Contreras, V., Custodio, N., Dansilio, S., la Cruz-Puebla, M. D., de Souza, L. C., Diaz, M. M., Duque, L., Farías, G. A., Ferreira, S. T., Guimet, N. M., Kmaid, A., Lira, D., Lopera, F., Meza, B. M., Miotto, E. C., Nitrini, R., Nuñez, A., O'Neill, S., Ochoa, J., Pintado-Caipa, M., Resende, E. D. P. F., Risacher, S., Rojas, L. A., Sabaj, V., Schilling, L., Sellek, A. F., Sosa, A., Takada, L. T., Teixeira, A. L., Unaucho-Pilalumbo, M. & Duran-Aniotz, C., Feb 2023, In: Alzheimer's and Dementia. 19, 2, p. 721-735 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Effects of the Pandemic and Confinement Measures on Mental Health in Chilean Children

Escobar, M. J., Panesso, C., Chalco, E. F., Cardemil, A., Grez, A., del Río, P., del Río, J. P., Vigil, P. & Duran-Aniotz, C., 2023, In: Psykhe. 32, 2, p. 1-14 14 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Genetic overlap between cortical brain morphometry and frontotemporal dementia risk

Diaz-Torres, S., Ogonowski, N., García-Marín, L. M., Bonham, L. W., Duran-Aniotz, C., Yokoyama, J. S. & Rentería, M. E., 15 Jun 2023, In: Cerebral Cortex. 33, 12, p. 7428-7435 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Latin American women in dementia research: outstanding contributions, barriers, and opportunities from Argentinian, Chilean, and Colombian colleagues

Fittipaldi, S., Baez, S., Gonzalez-Silva, C. & Duran-Aniotz, C., 2023, In: Frontiers in Aging Neuroscience. 15, 1168414.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Promoting diversity and overcoming publication barriers in Latin American neuroscience and Alzheimer's disease research: A call to action

Lourenco, M. V., Borelli, W. V., Duran-Aniotz, C., Zimmer, E. R. & de Castro, S. S., 1 Jan 2023, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 9, 1, e12378.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis

Duran-Aniotz, C., Poblete, N., Rivera-Krstulovic, C., Ardiles, Á. O., Díaz-Hung, M. L., Tamburini, G., Sabusap, C. M. P., Gerakis, Y., Cabral-Miranda, F., Diaz, J., Fuentealba, M., Arriagada, D., Muñoz, E., Espinoza, S., Martinez, G., Quiroz, G., Sardi, P., Medinas, D. B., Contreras, D. & Piña, R. & 9 others, Lourenco, M. V., Ribeiro, F. C., Ferreira, S. T., Rozas, C., Morales, B., Plate, L., Gonzalez-Billault, C., Palacios, A. G. & Hetz, C., 5 Jul 2023, In: Molecular Therapy. 31, 7, p. 2240-2256 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

2022

Aged Cattle Brain Displays Alzheimer's Disease-Like Pathology and Promotes Brain Amyloidosis in a Transgenic Animal Model

Moreno-Gonzalez, I., Edwards, G., Morales, R., Duran-Aniotz, C., Escobedo, G., Marquez, M., Pumarola, M. & Soto, C., 31 Jan 2022, In: Frontiers in Aging Neuroscience. 13, 815361.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Allostatic-Interoceptive Overload in Frontotemporal Dementia

Birba, A., Santamaría-García, H., Prado, P., Cruzat, J., Ballesteros, A. S., Legaz, A., Fittipaldi, S., Duran-Aniotz, C., Slachevsky, A., Santibañez, R., Sigman, M., García, A. M., Whelan, R., Moguilner, S. & Ibáñez, A., 1 Jul 2022, In: Biological Psychiatry. 92, 1, p. 54-67 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Associations of body mass index and sarcopenia with screen-detected mild cognitive impairment in older adults in Colombia

O’Donovan, G., Sarmiento, O. L., Hessel, P., Muniz-Terrera, G., Duran-Aniotz, C. & Ibáñez, A., 18 Oct 2022, In: Frontiers in Nutrition. 9, 1011967.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Multiscale entropy analysis of retinal signals reveals reduced complexity in a mouse model of Alzheimer’s disease

Araya-Arriagada, J., Garay, S., Rojas, C., Duran-Aniotz, C., Palacios, A. G., Chacón, M. & Medina, L. E., Dec 2022, In: Scientific Reports. 12, 1, 8900.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer’s Disease

Espinoza, S., Grunenwald, F., Gomez, W., García, F., Abarzúa-Catalan, L., Oyarce-Pezoa, S., Hernandez, M. F., Cortés, B. I., Uhrig, M., Ponce, D. P., Durán-Aniotz, C., Hetz, C., Sanmartín, C. D., Cornejo, V. H., Ezquer, F., Parra, V., Behrens, M. I., Manque, P. A., Rojas-Rivera, D. & Vidal, R. L. & 2 others, Woehlbier, U. & Nassif, M., 1 Jun 2022, In: Cells. 11, 12, 1860.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The burden of mild cognitive impairment attributable to physical inactivity in Colombia

O’Donovan, G., Lee, I. M., Hamer, M., García-Garro, P., Duran-Aniotz, C., Ibáñez, A., Sarmiento, O. L. & Hessel, P., Dec 2022, In: European Review of Aging and Physical Activity. 19, 1, 28.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

The Latin American Brain Health Institute, a regional initiative to reduce the scale and impact of dementia

Duran-Aniotz, C., Sanhueza, J., Grinberg, L. T., Slachevsky, A., Valcour, V., Robertson, I., Lawlor, B., Miller, B. & Ibáñez, A., Sep 2022, In: Alzheimer's and Dementia. 18, 9, p. 1696-1698 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging

Cabral-Miranda, F., Tamburini, G., Martinez, G., Ardiles, A. O., Medinas, D. B., Gerakis, Y., Hung, M. L. D., Vidal, R., Fuentealba, M., Miedema, T., Duran-Aniotz, C., Diaz, J., Ibaceta-Gonzalez, C., Sabusap, C. M., Bermedo-Garcia, F., Mujica, P., Adamson, S., Vitangcol, K., Huerta, H. & Zhang, X. & 9 others, Nakamura, T., Sardi, S. P., Lipton, S. A., Kennedy, B. K., Henriquez, J. P., Cárdenas, J. C., Plate, L., Palacios, A. G. & Hetz, C., 17 Nov 2022, In: EMBO Journal. 41, 22, e111952.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

2021

Amyloid pathology arrangements in Alzheimer’s disease brains modulate in vivo seeding capability

Duran-Aniotz, C., Moreno-Gonzalez, I., Gamez, N., Perez-Urrutia, N., Vegas-Gomez, L., Soto, C. & Morales, R., Dec 2021, In: Acta Neuropathologica Communications. 9, 1, 56.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

DEF8 and Autophagy-Associated Genes Are Altered in Mild Cognitive Impairment, Probable Alzheimer's Disease Patients, and a Transgenic Model of the Disease

Leyton, E., Matus, D., Espinoza, S., Benitez, J. M., Cortés, B. I., Gomez, W., Arévalo, N. B., Murgas, P., Manque, P., Woehlbier, U., Duran-Aniotz, C., Hetz, C., Behrens, M. I., Sanmartín, C. D. & Nassif, M., 2021, In: Journal of Alzheimer's Disease. 82, s1, p. S163-S178

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Retinal Ganglion Cells Functional Changes in a Mouse Model of Alzheimer's Disease Are Linked with Neurotransmitter Alterations

Araya-Arriagada, J., Bello, F., Shivashankar, G., Neira, D., Durán-Aniotz, C., Acosta, M. L., Escobar, M. J., Hetz, C., Chacón, M. & Palacios, A. G., 2021, In: Journal of Alzheimer's Disease. 82, s1, p. S5-S18

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates

Morales, R., Bravo-Alegria, J., Moreno-Gonzalez, I., Duran-Aniotz, C., Gamez, N., Edwards, G. & Soto, C., Oct 2021, In: Molecular Psychiatry. 26, 10, p. 5690-5701 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2020

Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer’s Disease

Flores-Muñoz, C., Gómez, B., Mery, E., Mujica, P., Gajardo, I., Córdova, C., Lopez-Espíndola, D., Durán-Aniotz, C., Hetz, C., Muñoz, P., Gonzalez-Jamett, A. M. & Ardiles, Á. O., 19 Mar 2020, In: Frontiers in Cellular Neuroscience. 14, 46.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

GERO Cohort Protocol, Chile, 2017–2022: Community-based Cohort of Functional Decline in Subjective Cognitive Complaint elderly

Slachevsky, A., Zitko, P., Martínez-Pernía, D., Forno, G., Court, F. A., Lillo, P., Villagra, R., Duran-Aniotz, C., Parrao, T., Assar, R., Orellana, P., Toledo, C., Rivera, R., Ibañez, A., Parra, M. A., González-Billault, C., Amieva, H. & Thumala, D., Dec 2020, In: BMC Geriatrics. 20, 1, 505.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer’s disease

Morales, R., Duran-Aniotz, C., Bravo-Alegria, J., Estrada, L. D., Shahnawaz, M., Hu, P. P., Kramm, C., Morales-Scheihing, D., Urayama, A. & Soto, C., Dec 2020, In: Acta Neuropathologica Communications. 8, 1, 213.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

La respuesta a proteínas mal plegadas como blanco terapeútico en la enfermedad de Alzheimer

Translated title of the contribution: Unfolded protein response as a target in the treatment of Alzheimer's diseaseRivera-Krstulovia, C. & Duran-Aniotz, C., Feb 2020, In: Revista Medica de Chile. 148, 2, p. 216-223 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The impact of sars-cov-2 in dementia across latin america: A call for an urgent regional plan and coordinated response

Ibanez, A., Santamaria-Garcia, H., Barragan, A. G., Kornhuber, A., Ton, A. M. M., Slachevsky, A., Teixeira, A. L., Meza, B. M. M., Serrano, C. M., Cano, C., Gonzalez, C. A., Gonzalez-Billault, C., Butler, C., Bustin, J., Duran-Aniotz, C., Acosta, D., Matallana, D. L., Acosta-Alvear, D., Trépel, D. & Resende, E. D. P. F. & 28 others, de Oliveira, F. F., Ibanez, F., De Felice, F. G., Navarrete, G., Tarnanas, I., Meier, I. B., Smid, J., Llibre-Guerra, J., Llibre-Rodriguez, J. J., Fajersztajn, L., Takada, L. T., Duque, L., de Oliveira, M. O., Bicalho, M. A. C., Behrens, M. I., Pintado-Caipa, M., Parra, M., Wilson, M. Z., De La CruPuebla, M., Custodio, N., Santibanez, R., Serafim, R. B., Tavares, R. M., Escudero, S. D. P., Rodriguez, T. L., Dawson, W., Miller, B. L. & Kosik, K. S., 2020, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 6, 1, e12092.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2017

IRE1 signaling exacerbates Alzheimer’s disease pathogenesis

Duran-Aniotz, C., Cornejo, V. H., Espinoza, S., Ardiles, Á. O., Medinas, D. B., Salazar, C., Foley, A., Gajardo, I., Thielen, P., Iwawaki, T., Scheper, W., Soto, C., Palacios, A. G., Hoozemans, J. J. M. & Hetz, C., 1 Sep 2017, In: Acta Neuropathologica. 134, 3, p. 489-506 18 p.

Research output: Contribution to journal › Article › peer-review

151 Scopus citations

2016

Role of prion replication in the strain-dependent brain regional distribution of prions

Hu, P. P., Morales, R., Duran-Aniotz, C., Moreno-Gonzalez, I., Khan, U. & Soto, C., 10 Jun 2016, In: Journal of Biological Chemistry. 291, 24, p. 12880-12887 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Strain-dependent profile of misfolded prion protein aggregates

Morales, R., Hu, P. P., Duran-Aniotz, C., Moda, F., Diaz-Espinoza, R., Chen, B., Bravo-Alegria, J., Makarava, N., Baskakov, I. V. & Soto, C., 15 Feb 2016, In: Scientific Reports. 6, 20526.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2015

ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related disorders

Torres, M., Matamala, J. M., Duran-Aniotz, C., Cornejo, V. H., Foley, A. & Hetz, C., 2 Sep 2015, In: Virus Research. 207, p. 69-75 7 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Titration of biologically active amyloid-β seeds in a transgenic mouse model of Alzheimer's disease

Morales, R., Bravo-Alegria, J., Duran-Aniotz, C. & Soto, C., 23 Mar 2015, In: Scientific Reports. 5, 9349.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

2014

Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease

Duran-Aniotz, C., Morales, R., Moreno-Gonzalez, I., Hu, P. P., Fedynyshyn, J. & Soto, C., 12 Feb 2014, In: PLoS ONE. 9, 2, e89014.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Brains from non-Alzheimer's individuals containing amyloid deposits accelerate Aβ deposition in vivo

Duran-Aniotz, C., Morales, R., Moreno-Gonzalez, I., Hu, P. P. & Soto, C., 27 Jan 2014, In: Acta Neuropathologica Communications. 2, 1, 76.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2013

Amyloid aggregates: Role in protein misfolding disorders

Translated title of the contribution: Amyloid aggregates: Role in protein misfolding disordersDuran-Aniotz, C., Moreno-Gonzalez, I. & Morales, R., Apr 2013, In: Revista Medica de Chile. 141, 4, p. 495-505 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Lack of prion transmission by sexual or parental routes in experimentally infected hamsters

Morales, R., Pritzkow, S., Hu, P. P., Duran-Aniotz, C. & Soto, C., Sep 2013, In: Prion. 7, 5, p. 412-419 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

The immunological response and post-treatment survival of DC-vaccinated melanoma patients are associated with increased Th1/Th17 and reduced Th3 cytokine responses

Durán-Aniotz, C., Segal, G., Salazar, L., Pereda, C., Falcón, C., Tempio, F., Aguilera, R., González, R., Pérez, C., Tittarelli, A., Catalán, D., Nervi, B., Larrondo, M., Salazar-Onfray, F. & López, M. N., Apr 2013, In: Cancer Immunology, Immunotherapy. 62, 4, p. 761-772 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2012

De novo induction of amyloid-β deposition in vivo

Morales, R., Duran-Aniotz, C., Castilla, J., Estrada, L. D. & Soto, C., Dec 2012, In: Molecular Psychiatry. 17, 12, p. 1347-1353 7 p.

Research output: Contribution to journal › Article › peer-review

153 Scopus citations

Protein misfolding cyclic amplification of infectious prions.

Morales, R., Duran-Aniotz, C., Diaz-Espinoza, R., Camacho, M. V. & Soto, C., Jul 2012, In: Nature protocols. 7, 7, p. 1397-1409 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

109 Scopus citations

Claudia Duran-Aniotz, PhD

Research output

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